David RandallbackResearcher Profile

David Randall

Job Title: Professor Zoology
Employer: University of British Columbia
Place of Birth: London, England
Public School attended: William Torbit school
High School attended: Ilford County High
Further Education: Southampton University (B.Sc., Ph.D.).
Geographic focus of research: BC, Nova Scotia, Newfoundland, UK, USA, China (PRC and Hong Kong), Singapore, Malaysia, Kenya, Brazil, Estonia, Lithuania

Brief synopsis of current research:
The regulation of ammonia production and excretion in fish. Aquatic toxicity of ammonia and hypoxia. The relationship of hemoglobin structure to oxygen and carbon dioxide transfer and tissue oxygen levels. Cellular responses of fish to hypoxia, including the role of hypoxia inducing factor and erythropoietin in responses to hypoxia.



Recent Publications:

Randall, D.J., J.M. Wilson, K.W. Peng, T.W.K. Kok, S.S.L. Kuah, S.F. Chew, T.J. Lam and Y.K. Ip, 1999. The mudskipper, Periophthalmodon schlosseri, actively transports NH4+ against a concentration gradient. Am. J. Physiol 277 (Regulatory and Integrative Comp. Physiol.) 46: R1562-R1567

Burgetz, I.J., Rojas-Vargas, R., Hinch, S.G. and Randall, D.J. (1998) Initial recruitment of anaerobic metabolism during sub-maximal swimming in rainbow trout (Oncorhynchus mykiss). J exp. Biol. 201:2711-2721.

Randall, D.J., Connell, D.W., Yang, R. and Wu, S.S. (1998) Concentrations of persistent lipophilic compounds in fish are determined by exchange across the gills, not through the food chain. Chemosphere. 137: 1263-1270.

Randall, D.J. (1998). Factors influencing the optimization of hemoglobin oxygen transport in fish. In: Principles of Animal Design: The optimization and symmorphosis debate. E.R. Weibel, C.R.Taylor and L. Bolis. Eds. Cambridge University Press, Cambridge, UK. 195- 201.

Pelster, B., and Randall, D.J. (1998) The physiology of the Root effect. In Fish Physiology Vol 17. Perry, S.F. and Tufts, B. eds. W.S.Hoar, D.J.Randall, and A.P. Farrell, series editors. Academic Press. New York. 113-139.

Canadian scientists interested in aquatic biology enjoy a well deserved international reputation and aquatic biology is one of the strengths of Canadian science. This is perhaps not surprising because much of the worlds freshwater is in Canada, and this country (or Russia) must have the longest marine coastline. Unfortunately there are only a few Marine biological stations and much is still unknown about our aquatic environment.